The ministry started in 1992 as Sharyn Cosby Ministries, Inc., an outreach working in the margins. The team of committed individuals traveled extensively to churches holding revivals, evangelizing, and winning souls for Christ. Additionally, they held worship services in various Oklahoma Department of Corrections and Juvenile Justice facilities. Cosby also worked with the Oklahoma Board of Corrections and was instrumental in prison reentry programming. Additionally, the ministry was actively engaged in street gang ministry and experienced many successes with that population. The ministry name changed to In the Spirit Ministries in 2002 and continued its evangelistic ministry.

      In 2007, in her living room, Apostle Cosby and five other people founded In the Spirit Christian Church (Disciples of Christ). The church was later chartered in 2008, and has since grown to a viable community of worshipers in Tulsa, Oklahoma. It is a diverse community that seeks to live out its vision to "impact and transform individuals and families by teaching practical biblical principles that is applicable to everyday life." The church offers a variety of ministries for all age groups and is an active presence in the community.

     To further the vision, Oklahoma Family Empowerment Center (OFEC), a counseling and social justice center, was founded in 2012 as an outreach of the church. It now stands as a separate but related 501(c)(3) organization. Under her direction, OFEC offers many services, including services for the homeless, food pantry, at-risk youth programming, seniors, and parenting classes.

      In The Spirit Training Institute was started in 2019 with the goal to training lay leaders and offer bible classes for those who desire to learn more than what they would receive in a worship service or faith formation class. Finally,  Living In The Spirit Talk Show and Podcast begin its broadcast in 2021, seeking to address theology and social justice in action.